28 05 2022

Updates from the OLEAF4VALUE project

The University of Florence, together with the National Research Council (CNR) and NATAC BIOTECH has presented a study on solid dispersions and oleanolic acid titled “Solubility and Permeability Enhancement of Oleanolic Acid by Solid Dispersion in Poloxamers and γ-CD” in the frame of the OLEAF4VALUE project.

The study has been published in Molecules, an open access journal of MDPI and is available online in this link.

Also related to the OLEAF4VALUE project, the University of Florence presented the thesis of Dr Chiara De Stefani on the preparation of microemulsions to deliver Oleanolic acid and triterpenoids extract at the XXX Congresso Nazionale di Fitoterapia Siena, 20-22 may 2022. The study has yielded a significant increase in the solubility and permeability of these compounds and evaluated the in vitro activity of formulations on the RAW 264.7 cell line. The study will be presented as a poster and it will participate in the Monti Prize at the same congress, which will be awarded to the best study presented by an author under 35 during the congress.